Journal: Materials Today Bio
Article Title: Honokiol-loaded nanoparticles for targeted bacterial eradication and treatment of MRSA infection
doi: 10.1016/j.mtbio.2025.102562
Figure Lengend Snippet: Effect of HNK@RHL-COS NPs on murine bacterial peritonitis. (A) Schematic diagram of the experimental process of in vivo bacterial peritonitis. The total bacterial load in the ascites (B), extracellular bacteria (C), and intracellular bacteria (D) of each group (n = 6). (E) H&E staining of liver, heart, spleen, lung and kidney (green: cell necrosis; yellow: increased erythroid cells; blue: granulocyte cells increased; black: fibroblast hyperplasia; dark green: alveolar epithelial cell hyperplasia; purple: cellular degeneration). NO (F), IL-1β (G), IL-6 (H) and TNF-α (I) levels after different treatments (n = 6). (J) In vivo imaging at different times after Cy5.5@RHL-COS injection. Statistical significance is denoted as ∗ p < 0.05, ∗∗ p < 0.01, and ∗∗∗ p < 0.001 vs the model group and # p < 0.05, ## p < 0.01, and ### p < 0.001 vs the control group.
Article Snippet: Sulfo-Cyanine 5.5 (Cy5.5) was obtained from MedChemExpress (New Jersey, USA).
Techniques: In Vivo, Bacteria, Staining, In Vivo Imaging, Injection, Control